MAbsorbent A2P HF

£576.00£4,965.00

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SKU: 3903 Category:

Description

MAbsorbents® were developed to mimic the Phe-132, Tyr-133 dipeptide binding site in the hydrophobic core structure of Protein A. We have developed IgG binding ligand libraries using a triazine scaffold substituted with aromatic amines. The resultant synthetic bifunctional ligands exhibit high affinities for human immunoglobulin G. Hence, MAbsorbent® A2P and A2P LL provide excellent purification performance.

MAbsorbents® effectively bind a wide variety of human and mammalian polyclonal antibodies (including bovine, mouse, sheep, goat, horse and rabbit) as well as whole monoclonal antibodies, humanized antibody chimeras and antibody fragments.

MAbsorbent® A2P P6HF LL is recommended for purification of IVIG (Intravenous Immunoglobulin) from Plasma and MAbsorbent® A2P P6HF for human or humanized antibodies.

Please contact us for pricing for pack sizes of 1 litre or more.

Additional information

Weight N/A
Dimensions cm
Ligand

Synthetic aromatic triazine derivative

Absorbent appearance

Pink

Base Matrix

Highly cross-linked 6% near monodisperse agarose (PuraBead 6HF)

Particle Size

90 ± 10µm

Binding Capacity

> 35 mg human IgG/ ml 20 to 30 mg MAb/ml

Opertating Pressure

Up to 3 bar (45 psi)

Operational flow rate

Up to 500 cm/hr with column diameter < 3cm Up to 200 cm/hr with column diameter > 5cm

Operating pH

pH2 to pH 14 (intermittent)

Chemical Stability

Stable in all commonly used buffers and solutions

Sanitization

0.5 to 1.0M NaOH, 25◦C

Storage

2-30◦C, 20% Ethanol

Product Documentation

MAbsorbent® A2P HF & HF LL Technical User Guide   MAbsorbent A2P P6HF PC3903 SDS Issue 2