Albumin Fusion Proteins

Human serum albumin (HSA) has a vast array of applications within the biopharmaceutical industry, including as a fusion partner to extend the half-life of a protein drug whilst maintaining its activity.

In order to support the rising production of a wide range of recombinant albumin fusion proteins, an affinity matrix has been developed that is highly stable, robust, non-toxic and provides high binding capacity, recovery and purity: ALBUPURE®

AlbuPure®, developed in partnership with Albumedix and manufactured exclusively by Prometic Bioseparations Ltd (PBL), is a high performance affinity chromatography adsorbent that is highly stable, robust and non-toxic providing high binding capacity, recovery and selectivity for albumin fusion proteins.

AlbuPure® combined with Albumedix’ Veltis® expression technology provides a complete albumin fusion purification package, available in a variety of formats to suit application and scale required.

Find out more about Albumedix’ Veltis® expression technology. 

Albupure® has the following key features:

  • Suitable for a wide range pf recombinant albumin-fusion proteins
  • Novel synthetic triazine ligand
  • Excellent flow properties
  • High dynamic binding capacity
  • Robust and long life adsorbent
  • Sanitizable using Sodium Hydroxide
  • Colourless ligand
  • Easy to pack
  • Manufactured to ISO9001 accredited standard
  • Single batches produced of up to 275 litres
  • Supported with a comprehensive Regulatory Support File (includes leachables and extractables)