Prometic Bioseparations Ltd (PBL) has long been established as an expert in affinity chromatography and bioseparations, specifically the large-scale purification of proteins (native and recombinant) and the elimination of contaminants including pathogens. With 30 years experience in the development and large scale manufacture of chromatography media, Prometic Bioseparations is an ideal partner for biopharmaceutical and plasma derived therapeutics with a proven track record.
A total of 18 of Prometic’s adsorbents have been incorporated into FDA approved manufacturing processes which produce 12 approved pharmaceutical and medical products.
We can offer both standard ‘off-the-shelf’ adsorbents and bespoke adsorbents, which can be designed to meet specific purification/ manufacture criteria. We now also supply a range of ‘semi-disposable’ bioprocess columns – Evolve™ Bioprocess Columns.
Off the shelf adsorbents
Prometic has an extensive range of off-the-shelf bioseparation products, all available in a variety of formats to suit your requirements. Applications covered include:
- Albumin and Albumin fusion proteins
- Antibody and Antibody fragments
- General purification
- Glycoprotein separation
- Endotoxin removal
- Serine Protease removal
- Insulin & Insulin analogues
- Plasma Proteins
- Affinity adsorbent screening tools
Bespoke downstream purification
Prometic also offers bespoke services to identify or optimize an existing Prometic product. These include:
- 30 years’ experience and success
- Fully validated bespoke chromatography adsorbent
- All associated process conditions for your target biomolecule
- Maximum yield and purity
- Minimum number of process steps
- Screening Tools
The adsorbent uses bespoke chromatography designed to specifically target your desired biomolecule and application, or, alternatively, Prometic can develop and manufacture a completely new adsorbent to your own unique specification.