Insulin analogues are recombinant proteins, often produced in microbial expression systems and are commonly purified using a combination of downstream process steps such as reverse-phase HPLC, ion exchange or size exclusion chromatography.
Due to the growing demand to reduce the number of process steps and overall cost of purifying insulin analogues, Prometic Bioseparations Ltd (PBL), has developed a high performance synthetic ligand affinity chromatography adsorbent which is compatible with large-scale process applications.
Insulin Adsorbent shares the same chemistry as PBL’s proven Mimetic Ligand™ adsorbents and provides high yields and purities for naturally occurring forms of insulin and insulin analogues from a variety of sources and is alkali resistant, robust, non-toxic and is designed for use in cGMP manufacturing of biological molecules.
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